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Notes on GLP-1s, muscle, and strength after 40.

Practical, research-backed writing on muscle preservation during weight loss, protein for adults 35 and over, and strength training that respects the body you have today.

GLP-1 muscle preservation

How to strength train on a GLP-1

Resistance training 2–3 times per week is the load-bearing intervention for keeping muscle on Ozempic, Wegovy, Mounjaro, or Zepbound. Here's the minimum effective routine, the research behind it, and how to progress without heavier weights.

GLP-1 muscle preservation

How much protein do I need on a GLP-1?

Most adults on Ozempic, Wegovy, or Mounjaro need around 1.0 gram of protein per pound of body weight to preserve muscle. Here's the research, the per-meal math, and how to actually hit it when appetite is suppressed.

GLP-1 muscle preservation

How much muscle do you lose on Ozempic?

Up to 40% of weight lost on Ozempic, Wegovy, or Mounjaro can be lean mass, meaning muscle and bone, not just fat. Here's the research, what it means in practice, and how to preserve muscle on a GLP-1.